Dermatica vs curology

Curology versus Nurx. I currently get my tret from Curology. It's about $30 every other month for a 0.005% tret with 4% naicinimide and 2% azelaic acid. Nurx, who I get my birth control from, offers 0.025 up to .1 tret for $30 a month (only available in a 3 month supply so $90 every 3 months). I've heard complaints from people that Curology won ...

Dermatica vs curology. At Curology, we believe that you don't need a maximalist skincare routine to help you reach your skincare goals. In fact, a simple skincare routine will typically suffice. Here's what it should look like: Wash your face with your cleanser of choice. Treat your skin with your personalized prescription formula at night.

The Custom Bottle: Active ingredients in your prescription are determined by your dermatology provider on a person-by-person basis. Commonly used ingredient...

Acne is one of the most common skin conditions in the world. In 2016, 85 percent of the people participating …. Skincare Rejuvenation is your number 1 source for the best skincare reviews and tips. Find what's working, what to avoid, and where to get the best deals.Jun 30, 2023 · Our Curology review found a 4.3/5-star rating on Facebook based on 3,461 reviews, 4.6/5 stars on Reviews.io out of 1,030 reviews, and 4.2/5 stars on Influenster from 8,295 reviews. There are no official reviews to consult on the Curology website. On Influenster, 57% of customers gave Curology 5/5 stars. Before you click off of this Curology vs Lumin review, we'll feature a few salient points to help finalize your ultimate decision: Curology: Standard shipping costs $5. Doesn't provide international delivery outside of the U.S. Trial boxes will usually ship out within 1 to 3 business days.Below, this Rory vs Curology review will share the pricing details for 6 of their available plans: Hot flashes treatment: monthly costs $35. 3-month supply costs $30. Vaginal Dryness treatment: quarterly plan costs $60 per month. Latisse: quarterly plan costs $53. A monthly supply costs $110.Skinsei Synergistic Skincare, $45-$65. Pure Culture Beauty $100. Apostrophe Skincare, $25. The Buff, Starting at $42. Curology, Starts at $19.95 Per Month. Agency, starting at $60 for a two-month supply. Atolla, $69. SkinCeuticals Custom D.O.S.E., Price Varies. Function of Beauty, Starting at $24.99.If you're looking for an alternative to Curology in the UK, Dermatica is an ideal option. ... Don't miss out on any of our reviews or deals! Subscribe to our ...

We’ve told youa bit about us,nowit’s your turn. Start consultation. First month £24.99 £2.90. Personalised skincare solutions, designed by dermatologists, tailored to your skin’s unique needs and delivered to your door. 02 of 05 Curology Curology About: Curology is all about skincare from head to toe, offering prescription acne treatment for your face, body, and beyond. The service offers traditional all-over topical treatments, cleansers, body washes, and even medicated pimple patches for spot treatment.Here's an example of how to use tretinoin and niacinamide together. Step 1: Cleanse your face with a gentle cleanser and gently pat dry. Step 2: Apply niacinamide serum all over your face and wait a few minutes for it to absorb. Step 3: Apply tretinoin cream all over your face. Step 4: Apply your moisturizer.Regardless, when I looked at Goodrx for the cheapest Tret, the next most affordable was around $48, so the Nurx option was the cheapest I saw. :) I switched to Nurx from Curology and I find it far SUPERIOR. The blend from Curology was only slightly effective at 0.04% tretinoin. And this was after TWO YEARS.Dermatologist Dr Dray's top 5 HOLY GRAIL SKIN CARE PRODUCTS. The skin care products I CANNOT LIVE WITHOUT. What skin care products can you not live without...We're here for you. Say hi. Email us at [email protected]. Text us at (415) 200-2060.The complete Curology routine comes with 3-steps to skincare including a cleanser, your custom formula, and one of two moisturizers. Gentle Cleansers; The Curology Cleanser is a gentle one that promises not to clog pores and not to strip away essential oil protecting the skin's barrier. The cleanser features oat leaf extract for a calming effect.

On a tretinoin FB group I belong to, it seems everyone using online derms likes dermatica. I havent tried it, as it is typically compounded with other ingredients, and I like using my own preferred actives. ... At the time I was using Curology and didn't have a copy of my Rx. Have you run into this before when ordering from ADC?Differin I used for about 5 months, it did nothing for me but dry my skin out and make me sad. Curology, on the other hand, SAVED MY SKIN. I had hormonal acne and seriously, within a week of getting my bottle, my skin cleared up. I really can't recommend it enough. The trial is only $5, you should give it a go.For healthy and beautiful skin, get skincare customized for you from experts at Curology. IPAddress.com. Curology.co • Curology Custom Skin Care | Start Your Free Trial. Global Traffic Rank > 1M. Rank in the United States. 118,824. 79.9% Traffic Share. Safety/Trust. Unknown. Child Safety. Unknown. Registered. May 2015. 8 years old.Sulwhasoo Makeup Balancer. In three color-neutralizing shades (pink, purple, and green), this CC cream has a mix of lightly hydrating and drying ingredients to help balance moisture on oily skin. It has light-to-sheer coverage, making it great to wear by itself or with foundation. $55.00 via Sulwhasoo.Founded by Dr. David Lortscher, board-certified dermatologist and co-founder of Curology, Agency is guided by the belief that high quality, personal, and effective anti-aging skincare should be ...Jun 30, 2023 · Our Curology review found a 4.3/5-star rating on Facebook based on 3,461 reviews, 4.6/5 stars on Reviews.io out of 1,030 reviews, and 4.2/5 stars on Influenster from 8,295 reviews. There are no official reviews to consult on the Curology website. On Influenster, 57% of customers gave Curology 5/5 stars.

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How To Get Prescription Skincare Without A Dermatologist Or Doctor?! (The Dark Web? Curology? Dermatica? Apostrophe?)We break it all down.Curology: https://c...Differin. 3.7. Overall Score. Shop Differin. Compare Differin vs another brand. DESCRIPTION. Curology ( curology.com) is an extremely popular skin care brand which competes against brands like Glossier, Bath & Body Works and Kiehl's. View all brands. Curology has an overall score of 4.4, based on 75 ratings on Knoji.These spiky devices may bring torture instruments to mind, but they're said to help reduce the appearance of post-acne scars (and wrinkles, too). Micro-needling works by stimulating your skin's production of collagen and elastin. Basically, the microscopic punctures create pinpoint areas of "injury" on the skin, which kicks your skin ...Dime Beauty vs Curology: Side-by-Side Brand Comparison. Compare Curology vs. Dime Beauty side-by-side. Choose the best skin care brands for your needs based on 1,407 criteria such as free returns & exchanges, international shipping, curbside pickup, PayPal and debit & prepaid cards . Also, check out our full guide to the top 10 face care brandsI've been using Curology for awhile as an alternative (tret/clindamycin/azelaic) but my skin looked so much better with both Tretinoin and Soolantra, so I completed a consultation with Dermatica, and they are recommending Ivermectin/Niacinimide. I included the info about my Curology formula in my consultation, and they didn't indicate any ...

Here, we take a closer look at 12 brands winning the customized skin-care trend. Courtesy of brand. 1/12. Skin Inc. My Daily Dose. Skin Inc. brings technology from Japan to its savvy approach to ...Hyaluronic acid (HA) is a moisturizing ingredient that deeply hydrates skin. It's a humectant, which means it adds water to the skin by drawing moisture from the air and deeper layers of the skin. It can hold 1,000 times its weight in water.¹ It works by binding to water molecules to retain moisture in all parts of your body, like your eyes ...Here’s been my routine: PM-. Simple oil cleanser. Mad Hippie cream cleanser. Cerave PM moisturizer (wait 20 min) Aquaphor on corners of mouth/nose. Dermatica .025% tret / 4% hydroquinone (every 2-3 nights) Cerave moisturizer cream (the thicker one) TO marula oil.Clear rosacea for good with prescription skincare. Get a powerful formula to treat inflammation, rosacea spots and flare-ups, with visible results within 8 weeks. Prescribed by our dermatology team at the right strength for you. …Compare Curology.com vs Dermatica.co.uk to select the best Skin Care Brands for your needs. See the pros and cons of Dermatica vs Curology based on free returns & exchanges, international shipping, curbside pickup, PayPal, and more. Last updated on September 24, 2023.Chemical exfoliation is your ally in the fight against acne, but proceed with caution! Overdoing it will irritate your skin and make acne worse. Fortunately, there are lots of options, even for sensitive skin. One of the major benefits of chemical exfoliation: no need for aggressive scrubbing. Chemical exfoliants like glycolic acid (AHA) or ...Tretinoin is more potent.² One of the main differences between tretinoin and retinol is that tretinoin can get straight to work without needing to be converted to a different form first. Tretinoin can treat acne. While retinol and tretinoin both treat signs of aging, only tretinoin is proven to treat acne.With help from his tech-savvy brother, Glenn, and their mom, fellow dermatologist Dr. Nancy Satur, David founded Curology in 2014. Together, this dermatological family built and expanded Curology to become a cutting-edge telemedicine company that helps transform the way patients access clinically-proven and prescription skincare. Interested in ...

Dermatica is an online dermatology service that provides easy and affordable prescription skincare. The team is composed of dermatologists, pharmacists, GPs, researchers and scientists who use technology to assess the needs of the customer and prescribe them with the best treatment. This is all done online and your treatment is sent straight to ...

Find Deals. We review three of the best online skincare platforms with prescription treatments for acne, wrinkles, rosacea, dark spots, and more. What products do they offer and is it really better than OTC? I tried online derm Apostrophe and here’s what happened. 06/30/2021. I’ve had significant melasma for several years now. The dark brown patches form what I call “my continents” across my forehead and temples. It’s never bothered me too much, yet, I also resent having to color correct, use foundation and concealer to fully even out my ...In terms of overall effectiveness, the classic Proactiv system has 4.1 (out of 5) stars; Proactiv+ has 3.6 stars; and ProactivMD has 3.5 stars. Curology claims to have over nine 9,000 5-star reviews with 93% of customers reporting that their prescribed potion was effective. (And they have some impressive before-and-after photos on their ...My experience using Dermatica for a tretinoin prescription. Sign-up: required a photo ID; required an additional photo of you facing front and holding your hand in front of your face which was odd Interaction with Derm: Very little communication from my prescriber.277. 157. r/SkincareAddiction. Join. • 10 days ago. [Before&After] Went through 6 months of minocyline and epiduo forte, and 2 months of taking 10 mg isotretinoin with 500 mg of erythromycin daily. If ur acne is as severe as mine, no amount of external skincare will clear ur skin.Green tea extract. Green tea extract proves to be a powerful ally in the fight against skin aging. Topical applications with 2% to 3% green tea extracts have shown significant protection against skin photoaging,⁸ which is aging caused by exposure to UV light. This makes it a promising natural component in anti-aging skincare.Low strength retinol = 0.25% or 2X and 0.3% or 3X. Mid strength retinol= .5% or 5x. High strength retinol = 1% or 10x. Some products claim to be retinol 2.5% or retinol 3%, however most of these products are not formulated correctly and therefore are actually not very potent.See yourself transform. Personalized skincare designed to help you get results. 93% report effective* 5M+ treated. 9K+ 5-star reviewsFind Deals. Wonder how new acne treatments form Curology and Hers and Apostrophe compare to Proactiv? Learn how each can help you adopt a personalized approach to …SkinMedica Retinol Complex 1.0, $93. SkinMedica Retinol Complex 1.0 is a potent night cream with a lightweight, smooth texture. The key ingredients—vitamin A and retinols - take care of wrinkles while ceramides keep the face looking plumped and moisturized. This formula is also available in less potent strengths.

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statement for head covering for passport photo; does allstate insurance cover windshield replacement; low frequency noise to annoy neighbours; how much damage does a netherite sword doIn this video I share my experience with Rory and compare it to Curology, which I've been using for almost three years. Since I use Rory to purchase Latisse ...Take the guesswork out of finding your next SPF with The Sunscreen by Curology, a mineral formula with SPF 30 designed by dermatologists for acne-prone skin (but great for all skin types). Made to work with your custom Curology skincare routine, the lotion has a silky, non-greasy texture and leaves no white-cast—perfect for everyday wear. 19.8. Jaxon Lane. California-based brand Jaxon Lane counts Nick Jonas and Justin Theroux among its famous (and very well-groomed) fans. Although Korean skincare isn't new to U.S. beauty buffs, the ...Skinsei Synergistic Skincare, $45-$65. Pure Culture Beauty $100. Apostrophe Skincare, $25. The Buff, Starting at $42. Curology, Starts at $19.95 Per Month. Agency, starting at $60 for a two-month supply. Atolla, $69. SkinCeuticals Custom D.O.S.E., Price Varies. Function of Beauty, Starting at $24.99.Generic Retin-A Cream vs Subscription Derms like Curology / Skin&Me / Dermatica. Discussion. Close. Vote. Posted by 5 minutes ago. Generic Retin-A Cream vs Subscription Derms like Curology / Skin&Me / Dermatica. Discussion. So I see quite a lot of posts on SCA etc. about how amazing these Subscription derms are for £20 a month (which is quite ...Treat your dog with love and care! ️. how tall is coryxkenshin / snowflake ceo fired / dermatica cancel subscription. dermatica cancel subscription November 23, 2022BHA = salicylic acid, a common ingredient in products labeled anti-acne you find at drugstores. Salicylic acid comes in strengths from 0.5% to 2% over-the-counter. AHA = glycolic acid, lactic acid. There are several different kinds. They help reduce hyperpigmentation, increase collagen synthesis, and work well for dry skin types.Went from layers of BP or SA to Curology. I had noticed some change in my skin already when I switched cleansers, but WOW. Curology made a dramatic difference in my skin so so fast. The person who I was assigned to deal with is a little curt and sometimes seems robotic but both new formulations have been spot on.In this video I share my experience of using tretinoin for the first time, sourced from the Dermatica prescription skincare site.I also share my side effects...Hmm, I saw improvement at the 8-9 week mark and then I had peaked and it didnt improve much after that. You say your acne is worse than when you started...so that makes me think it's not working for you. ….

SkinMedica Retinol Complex 1.0, $93. SkinMedica Retinol Complex 1.0 is a potent night cream with a lightweight, smooth texture. The key ingredients—vitamin A and retinols – take care of wrinkles while ceramides keep the face looking plumped and moisturized. This formula is also available in less potent strengths.Curology About: Curology is all about skincare from head to toe, offering prescription acne treatment for your face, body, and beyond. The service offers traditional all-over topical treatments, cleansers, body …Trustpilot: 3.4/5 stars. Sitejabber: 1/5 stars. That said, thousands of customers are raving about Musely skincare products for how effective they are at diminishing imperfections. Because of this, some members felt a heightened level of confidence after applying their creams and peels.We recommend just skipping it altogether to be safe. 5. Toothpaste on zits. Toothpaste as a spot treatment is practically a right-of-passage for anyone struggling with acne — but this is a misconception. Toothpaste can irritate the skin around the pimple, making it look redder and angrier — not smaller.Your Skincare VS CurologyEveryone wants radiant, smooth, and blemish-free skin, but not all skincare routines are created equal. With so many options on the market, it can be challenging to determine which method is best for you. Curology is a personalized skincare service that's gained a lot of popularity in recent yeJul 31, 2023 · Green tea extract. Green tea extract proves to be a powerful ally in the fight against skin aging. Topical applications with 2% to 3% green tea extracts have shown significant protection against skin photoaging,⁸ which is aging caused by exposure to UV light. This makes it a promising natural component in anti-aging skincare. Proactiv. Three-step topical acne regimen. Prices start at $24.95/month. Subscriptions or a la carte purchases. 60-day money-back guarantee (refund won't include shipping/handling) "A+" rated and accredited by the BBB. In business for 25+ years. Proactiv is one of the best-known names in over-the-counter acne products, with over 20 million ...The main difference is you pay $10 more per month and the number of actives in the formula. With Curology you get 3 "active" ingredients, whereas with Agency you get 4. The additional ingredients with Agency are limited. My Curology formula has Tretinoin, Azelaic Acid, and Niacinamide. If I switched to Agency, then I would likely get Panthenol ...And that doesn’t include the cost for a dermatologist visit without insurance which can cost hundreds. The generic for Retin-A micro is $149. And that’s tretinoin alone where Curology customizes a prescription with 3 actives including azelaic acid, clindamycin, and a few others. hell0_human • 4 yr. ago.The Inkey List Retinol Serum. $9.99 — ingredient shoutout: squalane, retinol, hyaluronic acid. Surprise: retinol is an antioxidant — vitamin A, to be exact. This $10 serum has a decent concentration of retinol to help treat signs of aging. (Of course, prescription-strength retinoids like tretinoin are more heavy-duty.) Dermatica vs curology, Our Curology review found a 4.3/5-star rating on Facebook based on 3,461 reviews, 4.6/5 stars on Reviews.io out of 1,030 reviews, and 4.2/5 stars on Influenster from 8,295 reviews. There are no official reviews to consult on the Curology website. On Influenster, 57% of customers gave Curology 5/5 stars., The product feels kind of similar to Curology, though the formulation is thinner and more of a liquid than a balm. The most gentle cleanser (imo) without an oily or filmy residue. I find probiotics in a cleanser a bit B.S.,, but this gave me a very similar experience to the curology- creamy, low lather, ultra hydrating with a plump after effect ..., In terms of overall effectiveness, the classic Proactiv system has 4.1 (out of 5) stars; Proactiv+ has 3.6 stars; and ProactivMD has 3.5 stars. Curology claims to have over nine 9,000 5-star reviews with 93% of customers reporting that their prescribed potion was effective. (And they have some impressive before-and-after photos on their ..., Add the Dark Spot Formula and save $10 per month when you’re subscribed to both products. Get ongoing shipments of both products every 2 months for $130 ( $65 /month). Start your trial. 30-day trial. Subject to consultation. Subscription required. Unique, customized formulas prescribed by a licensed dermatology provider who knows your unique ... , Our 2% salicylic acid acne body wash is perfectly calibrated: it targets breakouts at the source while being gentle enough to use every day. The body wash is dermatologist-designed to work with the rest of your Curology routine! All of Curology's products are non-comedogenic, fragrance-free, dye-free, paraben-free, and hypoallergenic., Thought it would be useful for people in the UK who would be interested in a Curology type service to know that I got an email just today letting me know that Dermatica has launched. I just went through the consultation and for my concerns they've offered me adapalene+BP, clindamycin+tretinoin or tazarotene., For instance, Proactiv offers several different packages to suit all users. While Curology uses a customized approach to the acne problem, meaning professionals decide what the treatment is going to be. That said, when you sign up for auto-delivery, you can get the Proactiv 3-Step System for less than $20 per month., Hey guys! I am currently living in the UK but from Canada and moving back this year. I have a Dermatica prescription for my acne and it's helped a lot. The prescription is similar to Epiduo but for anyone who hasn't tried a personalised skincare company before, essentially I had sent them pics of my face & skin texture initially., SCORES / MINI-REVIEW (out of 20) Paula Choice 10% Azelaic Acid Booster. FaceTheory Azeclear Azelaic Acid Serum A15. The Ordinary Azelaic Acid Suspension 10%. Dermatica Azelaic Acid 20% Cream. Price (for 30ml) 1 (£37) - This might be a bit harsh but I feel the price, especially given the size and the quality of other products, is extortionate., Here’s an example of how to use tretinoin and niacinamide together. Step 1: Cleanse your face with a gentle cleanser and gently pat dry. Step 2: Apply niacinamide serum all over your face and wait a few minutes for it to absorb. Step 3: Apply tretinoin cream all over your face. Step 4: Apply your moisturizer., Tretinoin. Tretinoin, also called all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (or retinol) that increases cell turnover. Tretinoin when applied topically is used to treat mild to moderate acne (e.g., grades I-III), photodamaged skin, and keratinization disorders such as ichthyosis and keratosis follicularis., I personally do not see Curology as being very disruptive to US dermatology practices. Telemedicine is inherently limited, and Curology in particular only provides service for mild-moderate acne and anti-aging. A dermatology practice includes much more than this, and at least up to now there is no full substitute for that., Hey Peeps!Today I am doing a Curology vs MDacne review! These two Custom skin care lines are taking over the internet offering free month trials, cancellatio..., Curology. Cost: $5 trial, then $19 + shipping every month or $40 with free shipping every two months. Prescription: 4% azelaic acid, 4% niacinamide, 0.25% zinc pyrithione. Formulation: this formulation was the smoothest and felt most like a normal moisturizer to apply., Yes it is just plain tretinoin I received. Started with 0.025, a month later they sent 0.05. I have been getting the 4%hydroquinone and tretinoin and its been 4 weeks and I see 0 results. I used them for ~4 months before I moved out of the country, and had a really good experience with them., It took a couple reformulations, but I eventually worked up to my current formula of 0.09 Tretinoin, 5% Azelaic acid, 1% Clindamycin. My acne improved with every tret increase. I believe 0.14 is the highest Curology will go for tret; I think I’ll need at least 0.1 although this formula is fiiiinally getting rid of CCs (knock on wood)., The full (skincare) package. With your Dermatica subscription, you'll get: A personalised formula tailored to your goals. Delivery to your door every 28 days (approximately) Unlimited check-ins with our expert team. FROM £24 99 /MONTH. Start consultation. First month £24.99 £2.90., The first month is free. You just pay $4.95 for shipping (plus tax, if applicable). After that, you transition to your chosen subscription plan. You have 3 options here: The Curology Set ($59.90 + free shipping): Every 60 days, you receive a cleanser, a custom prescription, and moisturizer., 7 дек. 2022 г. ... Whether you're using Curology for acne or Agency for anti-aging skincare, we ensure each dermatology provider is equipped with extensive ..., The rich moisturizer is sold as part of our 3-step set, along with the cleanser and your custom formula, all for a total of $79.90 for a 2 month supply. That comes down to just $39.95 per month for dermatologist-recommended skincare customized for your unique skin concerns., Founded by Dr. David Lortscher, board-certified dermatologist and co-founder of Curology, Agency is guided by the belief that high quality, personal, and effective anti-aging skincare should be ..., Telemedicine startups such as Nurx, Apostrophe, Ro Derm (formerly Rory), Hers, Hims, Curology and Agency and are making tretinoin more accessible than the era in which a trip to a doctor was required. They’re also tapping into skinfluencers, investing in ads to even further get the word out about the products., Curology is more catered to acne. Agency the sister company is more catered to aging. Just remember the ingredients available for curology is more for acne, they may assist as some ingredients help with pigmentation, but if you want stronger prescription toward melasma, you're probably better off with agency or musely., Retinols lose some of their potency after 6-9 months, and those contained in an airless pump can be good for 1 year or more. So personally I would feel ok using it after the date, some potency may of been lost but the product should still perform well enough until you get a new formula. Regardless as a company Curology should take blame for ..., Dermatica offers adapalene and benzoyl peroxide, while Curology offers Vitamin C and zinc pyrithione. The other actives are the same. Maybe cross-post to …, If you're looking for an alternative to Curology in the UK, Dermatica is an ideal option. ... Don't miss out on any of our reviews or deals! Subscribe to our ..., Rating: 4.6 / 5. ★★★★★ 4.7/5. By some estimates, acne treatment is now a $10b market globally. While blemishes have always been an acute source of insecurity, the industry's growth ..., My experience using Dermatica for a tretinoin prescription. Sign-up: required a photo ID; required an additional photo of you facing front and holding your hand in front of your face which was odd Interaction with Derm: Very little communication from my prescriber. I didn't know my tretinoin dosage would increase over time and I still don't ..., Curology offers subscription services to its clients, which costs from 400 dollars to 99 dollars per shipment. On the other hand, Agency provides subscription services that range from 30 dollars to 74 dollars per shipment. Every little bit counts, and here you are, getting a respite of a total of 16 dollars in an estimate., Compare Curology vs. Makeup Artist's Choice side-by-side. Choose the best skin care brands for your needs based on 1,407 criteria such as Uplift financing, free returns & exchanges, international shipping, curbside pickup and PayPal . Also, check out our full guide to the top 10 face care brands. Know someone shopping for Curology or Makeup ..., These spiky devices may bring torture instruments to mind, but they're said to help reduce the appearance of post-acne scars (and wrinkles, too). Micro-needling works by stimulating your skin's production of collagen and elastin. Basically, the microscopic punctures create pinpoint areas of "injury" on the skin, which kicks your skin ..., Yes. However, given that Software's treatment plans use prescription-strength actives, we recommend you dial it back a bit at the start to see how your skin reacts. In most cases, Vitamin A (our most commonly prescribed ingredient) can't be used with other active ingredients for the first 3-4 weeks., Low strength retinol = 0.25% or 2X and 0.3% or 3X. Mid strength retinol= .5% or 5x. High strength retinol = 1% or 10x. Some products claim to be retinol 2.5% or retinol 3%, however most of these products are not formulated correctly and therefore are actually not very potent.